This reciprocal interaction suggests that the balance between NF-κB-driven inflammation and PPAR-α-mediated mitochondrial lipid oxidation may be significant for the progression from metabolic stress to endothelial dysfunction and the consequent cardiorenal injury.
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Dietary Modulation of Inflammatory and Oxidative Pathways in Type 2 Diabetes: Biomarkers and Cardiorenal Outcomes.
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