At 200 μg/mL, treatment with XZZTP resulted in inhibition rates of NO, TNF-α, and PGE2 in RAW 264.7 macrophages of 56.53% ( p < 0.05), 53.75% ( p < 0.01), and 48.49% ( p < 0.01), indicating a highly significant difference compared with the model group.
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The Underlying Pharmacological Mechanisms and Active Components of XZZTP in Modulating Bacterial Inflammation Elucidated by LC-MS/MS, Network Pharmacology, In Vitro Experiments, Molecular Docking, and Dynamics Simulations.
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