Single-loop versus double-loop reconstruction after pancreatoduodenectomy: Does it impact on the risk of postoperative pancreatic fistula?

Ann Hepatobiliary Pancreat Surg · 2026 · PMC13212024 · PMID 41844339

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borderline significantno p-value reported

Patients who underwent neoadjuvant treatment (either chemotherapy or chemoradiotherapy) exhibited a borderline significant increase in the risk of POPF with DL reconstruction.

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marginally significantno p-value reported

We observed a marginally significant reduction in the risk of POPF among patients who underwent SL reconstruction after neoadjuvant treatment.

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