Baseline serum cortisol as a prognostic biomarker for immune checkpoint inhibitor therapy in advanced gastric cancer.

Front Oncol · 2026 · PMC13212230 · PMID 42211498

Europe PMC DOI

hedged sentences

0.0500

closest p · 1.0× alpha

0.0500

boldest claim

The sentences

marginally significantP = 0.050actually significant

In multivariate analysis including variables with P<0.10 (cortisol and gender), high cortisol showed a marginally significant association with shorter PFS (HR = 1.64, 95% CI: 1.00–2.69, P = 0.050), and female gender remained an independent risk factor (HR = 1.59, 95% CI: 1.01–2.49, P = 0.044; Table 4 ).

also in 26,082 other papers

a trend toward significanceP = 0.050actually significant

Multivariate analysis confirmed high baseline cortisol as an independent prognostic factor for poorer OS (HR=2.03, 95% CI: 1.20–4.00, P = 0.035) and showed a trend toward significance for shorter PFS (HR=1.64, 95% CI: 1.00–2.69, P = 0.050).

also in 3,729 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.