Barely Significant
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Evaluation of Articular Cartilage in Knee Osteoarthritis Using Macromolecular Proton Fraction Mapping.

Magn Reson Med Sci · 2026 · PMC13217289 · PMID 41125392

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not yet significantno p-value reported
In early OA, proteoglycan loss occurs before gross structural changes, 34 potentially explaining why MPF showed sensitivity to mild OA in regions where T 2 * changes were not yet significant.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.