Remifentanil self-administration promotes circuit- and sex-specific adaptations within the prefrontal-accumbens pathways.

Front Cell Neurosci · 2026 · PMC13217821 · PMID 42222059

Europe PMC DOI

hedged sentence

0.0570

closest p · 1.1× alpha

0.0570

boldest claim

The sentences

marginally significantp = 0.057so close (0.05 < p ≤ 0.1)

Examination of release probability showed a marginally significant impact of remifentanil treatment on paired-pulse ratio at D1 PL-Core synapses [ ISI x Treatment : F (1.31, 52.28) = 3.485, p = 0.057].

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