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Silent Megacolon: Fulminant <i>Clostridioides Difficile</i> Infection Without Diarrhea Mimicking Acute Colonic Pseudo-Obstruction.

ACG Case Rep J · 2026 · PMC13218763 · PMID 42222613

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an increasing trendno p-value reported
difficile no longer has a diarrhea limited presentation with an increasing trend of more unusual presentations associated with constipation. 4 The Ogilvie syndrome, also called acute colonic pseudo-obstruction (ACPO) is a form of massive non-mechanical colonic dilation, typically seen in critical hospital admitted patients. 5 While colonic dilation secondary to toxic megacolon may be precipitated by CDI, presentation of CDI without diarrhea mimicking ACPO is exceptionally rare and diagnostically elusive.

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