Integrative multivariate genomic analysis reveals shared genetic determinants and druggable targets for vascular calcification.

Front Med (Lausanne) · 2026 · PMC13218890 · PMID 42221083

Europe PMC DOI

hedged sentence

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closest p · 0.0× alpha

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highly significantP = 1.50 × 10 –7actually significant

The trait pair exhibited a strong and highly significant genetic correlation ( r g = 0.8125, SE = 0.1547, P = 1.50 × 10 –7 ), empirically justifying their integration into a multivariate framework.

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