Autoantibodies to IL-1Ra and PGRN in severe COVID-19 are associated with inflammation-induced hyperphosphorylated antigen isoforms.

Nat Commun · 2026 · PMC13219524 · PMID 42204159

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partially significantno p-value reported

With PGRN hyperphosphorylation and paralleling antigen depletion in peripheral blood at baseline and during follow-up we only observed partially significant association with MCP-1/CCL2 and IL-27, respectively.

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