Comparative efficacy and safety of dual-combination vs. triple-combination antihypertensive therapies in hypertensive patients: an updated meta-analysis of randomized controlled trials.

Front Pharmacol · 2026 · PMC13219965 · PMID 42222159

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may be significantno p-value reported

Given the wide time span of the studies (1988–2025), there may be significant differences from existing research regarding blood pressure targets, diagnostic criteria, background care, adverse event reporting standards, and drug formulations.

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