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Chronic traumatic encephalopathy neuropathologic change is associated with highest stage limbic-predominant age-related TDP-43 encephalopathy.

J Neuropathol Exp Neurol · 2026 · PMC13220065 · PMID 42044052

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a notable trendno p-value reported
There is also a notable trend toward a higher proportion of LATE-NC stage 3 in RHI cases than in those without RHI exposure, though this association needs to be confirmed in a larger cohort.

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