Barely Significant
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Genome-wide mapping of stress-responsive lncRNA, uc.104, reveals the chromatin-mediated regulation of stress and plasticity-related genes in the hippocampus of chronic restraint rats.

Mol Brain · 2026 · PMC13220396 · PMID 42002767

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highly significantp < 0.0001actually significant
Our sample size justification is supported by prior work [ 25 ], which identified 57 differentially expressed ncRNAs in the hippocampus of stressed rats, with several showing highly significant differences ( p < 0.0001) using only 7–8 animals per group.

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