an increasing trendP = 0.039
Using the RoB-2 tool, only 22 (23.9%) published trials had a low risk of bias (Figure S3), with an increasing trend over time (OR: 1.09; P = 0.039).
Using the RoB-2 tool, only 22 (23.9%) published trials had a low risk of bias (Figure S3), with an increasing trend over time (OR: 1.09; P = 0.039).