PrP turnover in vivo and the time to effect of prion disease therapeutics.

PLoS Pathog · 2026 · PMC13221148 · PMID 42189860

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highly significantno p-value reported

Modeling indicated that the main effect of the ki-3F4-FFI genotype on proportion labeled peptide was highly significant (shown in Fig 4B ) while the interaction term between genotype and days of labeled chow was non-significant, implying no additional effect of ki-3F4-FFI beyond the first 2 days.

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