Multimodal analysis of cell-free DNA identifies epigenetic biomarkers for amyotrophic lateral sclerosis diagnosis and progression.

J Clin Invest · 2026 · PMC13221225 · PMID 42222887

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highly significantno p-value reported

Of these highly significant hits, the DMR associated with PON1 , the gene encoding Paraoxonase 1, exhibited the greatest change in methylation pattern.

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