Glucagon-like Peptide-1 Receptor Agonists and Colorectal Cancer Risk.

AACE Endocrinol Diabetes · 2026 · PMC13221934 · PMID 42221415

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a nonsignificant trendno p-value reported

The tirzepatide group (HR 0.84, 95% CI 0.69–1.01) and bariatric surgery group (HR 0.85, 95% CI 0.74–0.98) both showed a nonsignificant trend towards reducing obesity associated cancers. 50 A different retrospective cohort study utilizing the TriNetX Research Network propensity matched type 2 diabetics who were new users of GLP-1RAs to those who use other antihyperglycemic agents.

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