Donor-derived cell-free DNA associated with increased risk of chronic lung allograft dysfunction and mortality: Are absolute levels better than percentage?

J Heart Lung Transplant · 2026 · PMC13222714 · PMID 41619918

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a nonsignificant trendno p-value reported

In comparison, the mean % dd-cfDNA level was also significantly associated with death and severe CLAD/death (adjusted HR 1.36, 95% CI 1.04-1.80, p = 0.027) but showed a nonsignificant trend when predicting moderate-to-severe CLAD or death ( Table 2 ).

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