Exploration of miR-326 delivery via biocompatible polymeric nanoparticles in medulloblastoma: A preliminary study.

Mol Ther Nucleic Acids · 2026 · PMC13223927 · PMID 42233108

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a decreasing trendno p-value reported

10 A significant decrease in Nanog mRNA was observed across all MB cell lines after miR326-NP delivery, accompanied by a decreasing trend in Sox2 expression.

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an increasing trendno p-value reported

Differentiation, assessed by evaluating Tubb 3 mRNA expression was found significantly upregulated in D283, after 24 h treatment with miR326-NPs and protein levels showed an increasing trend, in all tested cell lines ( Figures 6 A and 6B).

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