Impact of semaglutide pretreatment on reproductive outcomes in women with overweight and obesity with infertility: a real-world multicenter cohort study.

Reprod Biol Endocrinol · 2026 · PMC13224514 · PMID 42001071

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borderline significantno p-value reported

In the overweight subgroup (BMI 25.0–29.9 kg/m2), the pregnancy rate was 12.5% in the semaglutide group versus 25.0% in controls (OR = 0.43, 95% CI 0.18–1.01, p = 0.048), indicating a borderline significant reduction.

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