A highly significant association of the AA allele of SLC28A3 rs7853758 with decrease of ACT was identified in a cohort of anthracycline-treated children including ALL patients (N = 218, OR = 0.46 (95% CI: 0.20–1.80); p = 0.058) ( Visscher et al., 2013 ).
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Pharmacogenomics of treatment toxicities in pediatric B-Cell ALL: toward safer precision therapy.
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