Integrated multi-omics characterization of SPTBN2 overexpression reveals its pro-tumorigenic role and immune microenvironment remodeling in colorectal cancer.

Front Cell Dev Biol · 2026 · PMC13226874 · PMID 42238893

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an increasing trendno p-value reported

SPTBN2 expression also differed across TNM clinical stages and showed an increasing trend from stage I to stage IV ( Figure 4b ), suggesting that higher SPTBN2 expression may track with disease advancement.

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