The fact that highly significant reductions in MACCE, all-cause mortality, and cardiac mortality were still observed despite this probable dilution of treatment effect strongly supports a robust biological advantage of ticagrelor in this high-thrombotic-risk population and validates the observed benefits.
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Ticagrelor Versus Clopidogrel in Patients With ST-Elevation Myocardial Infarction and Elevated Platelet Counts: A Multicenter Comparative Analysis of Ischemic Outcomes.
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