Quantitative comparison of methods for widespread delivery of small molecules across the blood-brain barrier.

Commun Biol · 2026 · PMC13230606 · PMID 41935136

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almost significantp = 0.07so close (0.05 < p ≤ 0.1)

TL and LPAR6 staining did not relate strongly to the MRI results, but staining for the ZO-1 tight junction protein displayed inverse correlations with the imaging data that were significant following US-mediated delivery ( p = 0.02, n = 10 ROIs) and almost significant after LPA-mediated delivery ( p = 0.07).

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