Solvent-accessible surface area (SASA) analysis indicated a decreasing trend for both complexes, with FDC–KPC-160 exhibiting a higher number of hydrogen bonds in the later simulation period (1–8 vs 1–5) ( Fig. 3B ).
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Characterization of KPC-160, a novel Ω-loop-deleted KPC variant on a dual-copy plasmid that confers cefiderocol resistance.
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