There was a decreasing trend in the amodiaquine/lumefantrine pfmdr1 N F SND haplotype in the Coastal zone.
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Spatial and temporal description of antimalarial drug resistance markers in Ghana using targeted amplicon deep sequencing.
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The sentences
There was an increasing trend in the temporal distribution of the wild-type CVMNK haplotype in all ecological zones, in contrast with the CQ-resistance-conferring CV IET haplotype.