Barely Significant
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The interplay between neuroinflammation and endothelial dysfunction in cerebral small vessel disease.

Front Immunol · 2026 · PMC13233265 · PMID 42253958

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a nonsignificant trendno p-value reported
It was associated with lower adherence and more frequent adverse events than placebo, and did not improve cognition, mental well-being, or blood pressure; only a nonsignificant trend toward reduced white matter hyperintensity progression was observed ( 92 ).

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