Comparison of pharmacovigilance and mechanism analysis of the vascular toxicity caused by platin-based chemotherapy: integration of FAERS analysis, network pharmacology, and endothelial validation.

Ther Adv Drug Saf · 2026 · PMC13234381 · PMID 42254651

Europe PMC DOI

hedged sentence

0.0010

closest p · 0.0× alpha

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boldest claim

The sentences

highly significantp < 0.001actually significant

A significant increase in cytotoxicity was observed with higher exposure time, with the 5 and 10 molar amounts becoming significant ( p < 0.05) and highly significant ( p < 0.001), respectively.

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