Efficacy and safety of once-weekly insulin efsitora alfa versus daily basal insulin analogs in type 2 diabetes: a systematic review and meta-analysis.

Subgroup analyses by prior insulin exposure showed borderline significance in insulin-naive patients (MD = 0.31, 95% CI: −0.01 to 0.62; P = 0.05) and no significant difference in insulin-experienced participants (MD = −0.06, 95% CI: −0.32 to 0.20; P = 0.25) (Supplemental Digital Content Figure S10, available at: http://links.lww.com/MS9/B192 ).

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