Severity and duration-dependent aortic stiffening in a rabbit coarctation model identifies constitutive material parameters as promising regional biomarkers for hypertension progression.

Strain energy as an empirical benchmark for CoA-induced arterial stiffening In the proximal aorta, there was a highly significant main effect of group (ANOVA p = 8.3 × 10−9), with post-hoc comparisons showing that all Prolonged CoA groups exhibited markedly elevated strain energy relative to controls (Fig. 1 ).

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