Rikkunshito ameliorates colonic dysfunction and hormonal imbalance in an IBS mouse model with modulation of transient receptor potential channel activity.

Front Pharmacol · 2026 · PMC13237641 · PMID 42256400

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a decreasing trendno p-value reported

Serotonin (5-HT) levels were elevated following zymosan treatment; although Rikkunshito administration did not result in a statistically significant reduction, a decreasing trend was observed compared with the untreated IBS group ( Figure 7Aa ).

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