Barely Significant
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A systematic review of the effectiveness, safety and acceptance of nicotine replacement therapy use for vaping cessation in youth aged 17 years or younger.

Syst Rev · 2026 · PMC13238082 · PMID 42026647

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might be significantno p-value reported
Second, existing vaping cessation support is predominantly based on smoking cessation models, however, there is limited data on the treatment of tobacco dependence in youth [ 39 ] and some evidence suggest there might be significant differences in dependence mechanisms for vaping and smoking, particularly in youth [ 74 ].

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