Barely Significant
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Adjunctive Use of Ozone Therapy in Treating Periodontitis in Smokers: A Prospective Split-Mouth Study.

Int J Dent · 2026 · PMC13240370 · PMID 42254884

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highly significantno p-value reported
In addition, a previous study reported a highly significant improvement in clinical parameters and bacterial counts in quadrants treated with SRP combined with ozone application compared with SRP alone in patients with aggressive periodontitis [ 29 ].

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