Feminizing and masculinizing gender-affirming hormone therapy affects fibrin clot characteristics in opposite directions.

Res Pract Thromb Haemost · 2026 · PMC13240812 · PMID 42254455

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a trend toward significanceP = .06so close (0.05 < p ≤ 0.1)

Between-group differences in relative changes (Δ0-12 months/0 months) were observed for MA ( P = .03), OHP ( P = .001), clot lysis ( P = .008), and fibrinogen ( P < 0.001), with a trend toward significance for V max ( P = .06; Figure ).

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