Oromucosal Administration of a Cannabidiol-Enriched Cannabis sp. Extract for 2 Weeks Moderately Reduces Cold Hyperalgesia in Rats With Neuropathic Pain.

Eur J Pain · 2026 · PMC13241296 · PMID 42248695

Europe PMC DOI

hedged sentence

0.4454

closest p · 8.9× alpha

0.4454

boldest claim

The sentences

a trend toward significancep = 0.4454not close (p > 0.1)

Unlike the effects observed on mechanical and cold sensitivity, treatment with the CBD‐enriched extract did not significantly improve heat thresholds in the hot plate test in CCI animals compared with the CCI + Veh group at Day 21, although females showed a trend toward significance (males: p = 0.4454; females: p = 0.0503).

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