Effects of obstructive sleep apnea on circulating immune cells profiles: Evidence from NHANES dataset and Mendelian randomization.

Braz J Otorhinolaryngol · 2026 · PMC13241890 · PMID 42224780

Europe PMC DOI

hedged sentences

0.0550

closest p · 1.1× alpha

0.0910

boldest claim

The sentences

borderline significancep = 0.055so close (0.05 < p ≤ 0.1)

Complete-case analysis within matched pairs (n = 2,205 non-OSA; n = 2,233 OSA) consistently replicated originally significant hematological findings (WBC, monocytes, neutrophils, MCV, platelets, SII; all p < 0.05), with only MCH showing borderline significance (p = 0.055).

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a trend towards significancep = 0.091so close (0.05 < p ≤ 0.1)

In addition, participants with OSA had significantly higher levels of SII (p < 0.05), with a trend towards significance in the NLR (p = 0.091).

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