Eight-year follow-up of phenotypic progression in a Chinese XLRP pedigree with a novel <i>RP2</i> gene mutation.

Although early-onset myopia was more common in children, there was a slightly increasing trend in annual progression; moreover, while the retinal structure did not differ statistically significantly, the ERG changes indicated a steadily decreasing trend.

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In general, the initial visual acuity remained almost stable or showed an increasing trend but still remained below the lowest limit of the age-standardized BCVA ( Supplementary Table S2 ); this progression exceeds the typical age-related vision improvement, potentially confirming the degenerative nature of RP2 -associated XLRP.

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