Immunogenetic HLA-DQ and IgG serological profiles in individuals with self-reported wheat/gluten sensitivity: a retrospective real-world evidence study.

Front Immunol · 2026 · PMC13243097 · PMID 42266680

Europe PMC DOI

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highly significantp = 0.001actually significant

3.2 The DQ8 marker The DQ8 allele exhibited a highly significant association ( X 2 = 10.24; p = 0.001), reinforcing its established role in the predisposition to gluten-related immune dysregulation.

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