Barely Significant
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Shunt Complications in Syndromic versus Non-Syndromic Pediatric Hydrocephalus: A Propensity-Matched Multicenter Analysis of 35,234 Patients.

Pediatr Neurosurg · 2026 · PMC13245943 · PMID 41428615

Europe PMCDOI
2
hedged sentences
0.0380
closest p · 0.8× alpha
0.0380
boldest claim

The sentences

a trend toward significancep = 0.038actually significant
Meanwhile, Down syndrome showed a modest risk increase (5.3%), with a trend toward significance (HR 2.59, p = 0.038), although the associated CIs were broad and crossed unity in other metrics.

also in 3,729 other papers

highly significantno p-value reported
In conditions like Arnold-Chiari and encephalocele, the rates of shunt dysfunction exceeded 30%, with OR above 3.0 and highly significant p values.

also in 132,142 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.