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Margin status after breast-conserving surgery for breast cancer in the Netherlands from 2009 to 2022.

BJS Open · 2026 · PMC13247999 · PMID 42263217

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a decreasing trendno p-value reported
An extensively positive margin (> 4 mm involvement) occurred in 3.9% of patients, with a decreasing trend seen until 2013.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.