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Comparison of 2 stereotactic radiotherapy regimens for brain metastases: Is higher always better?

Neurooncol Adv · 2026 · PMC13249077 · PMID 42273327

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39 Similarly, conclusions can be made regarding ICI and ICI-based combination, which showed a statistical trend. 40 In a retrospective cohort of 549 metastases treated with either monofractionated or hypofractionated SRS, spanning between 2013 and 2021, a statistical association was found between the PD-L1 status and the risk of RN. 41 Of note, we provide actualized data with a broader representation of new strategies (CT + ICI).

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