Ergothioneine as a potential protective agent against macular degeneration and other eye disorders.

Sci Rep · 2026 · PMC13249876 · PMID 41998200

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a decreasing trendno p-value reported

In the AH, a decreasing trend of ET was observed in AMD patients relative to cataractous patients (Fig. 4 A), however, these differences were not statistically significant.

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highly significantno p-value reported

Regardless, this highly significant decrease in serum ET suggests an association between ET and AMD, especially since the eye is known to accumulate ET.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.