Glucose-Responsive Dual-Enzyme Mimetic Nanoreactor Remodels Diabetic Periodontitis Microenvironment for Augmented Alveolar Bone Regeneration.

Int J Nanomedicine · 2026 · PMC13250248 · PMID 42281923

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a decreasing trendno p-value reported

Additionally, the HIF-1α protein, which typically accumulates under hypoxic conditions, also showed a decreasing trend in this group, indicating alleviation of the hypoxic state ( Figure 5i ).

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