Hepatocyte BDNF Acts as a Novel Immune Checkpoint to Restrain TLR4-Mediated Acute Hepatitis.

Importantly, random‐effects meta‐analysis of correlation coefficients demonstrated a strong and highly significant pooled inverse association between Bdnf and Ccl2 expression (overall effect size = −0.82, 95% CI −0.89 to −0.69; Z = −7.62, p < 0.001) (Figure 4B ).

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