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Evaluating comorbidity scoring systems for flumatinib therapy in chronic myeloid leukemia: a machine learning and SHAP-based predictive analysis.

Front Med (Lausanne) · 2026 · PMC13253388 · PMID 42292180

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highly significantno p-value reported
The multivariable model demonstrated that a severe CIRS-G score (≥8) remained an independent and highly significant predictor of 12-month therapy failure, whereas chronological age did not maintain independent statistical significance.

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