Barely Significant
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Real-world pharmacological treatment of patients with hyperemesis gravidarum in 9 cities of China from 2019 to 2024: a cross-sectional analysis.

Front Pharmacol · 2026 · PMC13254168 · PMID 42292800

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an increasing trendno p-value reported
The average age of patients showed no significant change, while the proportion of advanced maternal age cases exhibited an increasing trend, which may be associated with postponed childbearing intentions.

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a decreasing trendno p-value reported
The proportion of HG patients at 5–16 weeks showed a decreasing trend, while the proportion at 16–36 weeks showed an increasing trend ( Table 1 ). 3.2.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.