While both BS and DBS treatment groups induced a significant increase in the proportion of M1 macrophages (CD86 + gated on F4/80 + ) and a corresponding decrease in the M2 population (CD206 + gated on F4/80 + ), there was a notable trend suggesting that DBS treatment induced a stronger ratio of M1 to M2 macrophages compared to BS ( Fig. 4 e and f).
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A deformable <i>Bacillus subtilis</i> with gut homing for tumor treatment via bacterial metabolism-facilitated synergistic approach for starvation, chemotherapy, and immunotherapy.
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