Plasmacytoid dendritic cells alleviate atopic dermatitis by suppressing Th2 inflammation via the IFN-α/IFNAR1 pathway.

Front Immunol · 2026 · PMC13260283 · PMID 42292369

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an overall trendno p-value reported

As shown in the heatmap ( Figure 1A ), genes associated with cDC1, cDC2, pDC, and Th2 cells showed an overall trend toward upregulation in AD patients compared to HCs, whereas Treg markers showed variable changes.

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