Barely Significant
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Interferon-related inflammaging links epigenetic age acceleration to multimorbidity.

Cell Genom · 2026 · PMC13261661 · PMID 41999740

Europe PMCDOI
1
hedged sentence
0.0400
closest p · 0.8× alpha
0.0400
boldest claim

The sentences

marginal significancep = 0.04actually significant
In the reverse MR analysis, when treating EAAs as exposures and inflammatory proteins as outcomes, only two associations reached marginal significance (EAA_Pheno on CCL23 and IL-7) (CCL23: p = 0.04; IL-7: p = 0.049), arguing against a major role for reverse causation.

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