Barely Significant
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Endometrioid Intraepithelial Neoplasia in the Secretory Phase: Morphologic and Biomarker Diagnostic Features in a Common, Overlooked Setting.

Am J Surg Pathol · 2026 · PMC13263045 · PMID 41973882

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highly significantno p-value reported
29 These features of the study population are consistent with the inclusion criteria and prior data establishing a highly significant association between higher BMI and earlier age at EIN diagnosis. 28 Self-reported dates for last menstrual period (LMP) were on average 29.7 days prior (Table 1 ), consistent with most specimens being obtained in the secretory phase, with 14/34 (41.2%) patients reporting LMPs >28 days prior, suggesting ovulatory dysfunction or perimenopausal state. 30 The most frequent clinical diagnosis was AUB (not otherwise subclassified), with ovulatory dysfunction (AUB-O) as one of the attributed causes in 10/40 patients (25%) (see Table 1 legend for additional details).

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