Blocking β-alanine synthesis triggers widespread perturbations of energy and lipid metabolism in the brain.

Mol Metab · 2026 · PMC13265694 · PMID 42177944

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trend toward significanceno p-value reported

In the OB, GADL1 loss reduced carnitine levels, and several medium-to long-chain acylcarnitines showed a downward trend toward significance, suggesting altered substrate availability for mitochondrial fatty acid oxidation [ 44 ].

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